using self or me instead of only member

Does using self have influence on performance (there is no difference in size of app)?

So what is a better:

function class_func()

{

  self.class_member = 1;//self_ye

  me.class_member = 1;//self_me

  class_member = 1;//self_no

}

Profiler usually shows that faster is without self but form time to time (how to trust profiler?) I can see difference.