I've had pretty much the exact same issue with my Edge 500 and Edge 510.
Was working last week on OSX 10.10, now on OSX 10.11 and nothing.
My Fenix seems to sync just fine though.
Edge 1000 experiencing connection issues after El Captain update
Hi,
i'm experiencing the same issues, no connection with Mac.
I've tried different cables (connection ones of course) still charging the unit, but no icon on the screen indicating that the device is communicating with the computer.
I've tried everything but doesn't work.
Please fix the issue