I don't use my Garmin for navigating a saved course very often, but when I do, it gives me wrong turn by turn instructions. Since I generally know the direction I want to go in, I've figured out when it is wrong, but this would be a big problem if I was riding where I didn't know the area.
Most recent example, see photo, as I approach my next turn the Garmin is telling me to turn left, see upper corner. The audio ques say to turn left. If I turn left, I get the alert that I'm off course and need to do a U-turn. This example, you can see that as I got close to the turn, the main map was telling me to turn right (which was correct).
I have the latest software installed.
I find when I'm navigating a saved course, the Garmin will do this (tell me to turn the wrong way) about 30% of the time.