I am running an Assioma UNO with my Edge 540 for few months now. (I've had the UNO for a year and 540 for few months).
There were no issues until the 540 prompted to upgrade on 24th May 2024, since then I started noticing drop in connection with the UNO. And it seems like it's happening every 15-20mins or so.
I've had 2x long'ish ride since and it was happening on both rides.
Currently it's connected via BLUETOOTH
I'm still yet to try it on ANT+ - will update the post once I've tested this.