Ever since I started using the Beta software with my EDGE 530, Express for Mac can't sync my device.
I have to use device WIFI or Mobile Connect.
I get the following screenshot
Any advice? Express is up to date.

It should be the txt file. Make sure the date and time match the error message during the sync, That will provide verification that it is the right file. Then run a sync without disconnecting. It recreates the file after every power on, so the error will not disappear until you run the sync a second time. It will error out after every sync. This is just a workaround and Garmin would need to somehow resolve the issue with the creation of an invalid file.
Be cognizant of the date in time instead of just globally assuming it is an activity file. I backed up and deleted all the activity files and the error still persisted. You should be able to identify the file with the information presented in the dialogue box.