I ran 6K at 5:10 today (sad, I know ;)). My HR was more than double my resting HR for the whole 6K, triple for about 2K. I'm 192lbs.
My 310XT said I burned 220Cal. Two of the 1K laps were at 12Cal each. Clearly this is wrong. If it's wrong today, can I trust any of the calories counts from other days?