I am sorry that you are having trouble with Garmin Express. Are you trying to install the latest version of Garmin Express or the latest updates for your device in Garmin Express? If you are trying to update to the latest version of Garmin Express, try downloading the installer from www.garmin.com/express. If that does not solve the problem, try a full uninstall of Garmin Express before installing the new version.
If you are having trouble updating your device in Express, please visit the following FAQ:
What should I do if I'm having issues with the Garmin Express client?