Got a new Garmin for Christmas (to replace the one that was stolen from me on Dec.30th... long story) and, of course, downloaded the latest Garmin Express software, in this case being 7.2.20.
The installation went fine... but you cannot launch the app afterward, even in Administrator mode. Not on Windows 10, at any rate.
I read online that many have had similar issues so I went to the Garmin Express page and downloaded the 7.1.30 version which, when installed, run s just fine.
So, I thought that others could benefit from this as well. Good luck!