For a couple of months now I see the little blue dot in the top right corner of Garmin Connect indicating it wants to sync something with my Forerunner 220 (the same goes for Garmin Express in the device selection). Garmin Connect tells me it wants to sync device settings, Garmin Express says it wants to install new user settings. I haven't changed any settings on my Forerunner 220 in a long time. Yet this keeps happening when I connect the device to my PC. When I disconnect it the Forerunner does the little Updating animation for a second and goes back to normal. The whole thing doesn't seem to impair any functions, it's just a minor annoyance.
I'm using Windows 10 x64 and Garmin Express 5.8.0.0.