Tried to install this update onto a 64bit Windows10 setup (never had an issue with previous updates) and got an error message stating that this is an unsupported 16 bit application.
On two Win10 x64 AU machines here, Express 4.1.27 tells me that the update to 4.1.28 is available, but when I click on Install Now, the download progress bar jumps from zero to 100% in about a second and nothing further happens. This just seems a problem with the update mechanism in Express, as I was able to manually download the latest installer from the Garmin web site and run it, after which 4.1.28 was installed and ran successfully.