I have noticed a lot of people having issues trying to install Garmin Express on windows 10 systems. There is a pretty simple solution for this.
1) Download the Garmin Express installer.
2) Right Click the installer and select Properties.
3) Select the Compatibility Tab.
4) Check the box for "Run this program in compatibility mode for:"
5) Select Windows 8.
6) Click Apply and then OK
You should now be able to install Garmin Express on your computer without the installer failing.
I hope this helps, I've seen a lot of complaints about it and haven't seen anyone post a fix.