BaseCamp 4.2.2 is available at http://www8.garmin.com/support/download_details.jsp?id=4435.
It should be available from inside BaseCamp soon.
This is a maintenance release that addressing the most common issues of 4.2.1.
Change list
Fixed start-up issue when opening some map installations
Fixed start-up issue with opening Trip Planner
Fixed various issues with upgrading legacy databases
Fixed issue searching for named trails
Fixed activity based routing
Fixed issue with editing routes received from a device
Fixed issue when using find
Fixed issue with displaying graphs for tracks that don't contain elevation, time, or other data.